company news about Chengdu Youngshe NEW product: 2-mercaptonicotinoyl glycine (2-MNG)

Product name: 2-mercaptonicotinoyl glycine

Molecular Formula: C8H15NO2

Molecular weight: 157.2

Grade: Cosmetic grade

Usage: Sking whitening, lightening

Packing: 10g/bottle, 100g/bottle or 1kg/bag

Description:

2-mercaptonicotinoyl glycine is a molecule that addresses localized pigmentation issues that lead to age spots and post-acne marks. It works on all skin types and provides more even & natural skin tone by improving the appearance of dark spots.

Background
Chronic nonextreme sun exposure induces two mechanisms of skin pigmentation, causing immediate darkening and delayed tanning. A new molecule, 2-mercaptonicotinoyl glycine (2-MNG), has been shown in vitro to inhibit both immediate darkening and new melanin synthesis via covalent conjugation of the thiol group of 2-MNG to melanin precursors.

Results
2-MNG alone significantly reduced immediate darkening and inhibited new melanin production when compared with vehicle, with higher performance at 1% than at 0.5%. 2-MNG at 0.5% in association with LHA and MSX showed significantly higher performance than 2-MNG 0.5% alone. 2-MNG at 0.5% and 1% showed significantly better performance than 4-n-BR.